Events Calendar

Molecular Toxicology Journal Club

EOH student Emily Nicholls will present the article:

"Exposure to air pollution and scarlet fever resurgence in China: a six-year surveillance study"

Liu Y, Ding H, Chang ST, Lu R, Zhong H, Zhao N, Lin TH, Bao Y, Yap L, Xu W, Wang M, Li Y, Qin S, Zhao Y, Geng X, Wang S, Chen E, Yu Z, Chan TC, Liu S

Abstract

Scarlet fever has resurged in China starting in 2011, and the environment is one of the potential reasons. Nationwide data on 655,039 scarlet fever cases and six air pollutants were retrieved. Exposure risks were evaluated by multivariate distributed lag nonlinear models and a meta-regression model. We show that the average incidence in 2011-2018 was twice that in 2004-2010 [RR = 2.30 (4.40 vs. 1.91), 95% CI: 2.29-2.31; p < 0.001] and generally lower in the summer and winter holiday (p = 0.005). A low to moderate correlation was seen between scarlet fever and monthly NO2 (r = 0.21) and O3 (r = 0.11). A 10 μg/m3 increase of NO2 and O3 was significantly associated with scarlet fever, with a cumulative RR of 1.06 (95% CI: 1.02-1.10) and 1.04 (95% CI: 1.01-1.07), respectively, at a lag of 0 to 15 months. In conclusion, long-term exposure to ambient NO2 and O3 may be associated with an increased risk of scarlet fever incidence, but direct causality is not established.


PLEASE SUPPORT OUR STUDENT PRESENTERS

Organized by Dr. Nicholas Fitz of the Department of Environmental and Occupational Health, this weekly course is designed to expose EOH students to the newest and most exciting research in a diverse set of topics related to toxicology.  Guests are welcome.

Dial-In Information

Contact Dr. Nicholas Fitz (nffitz@pitt.edu) for Zoom information to attend.

Thursday, September 24 at 11:00 a.m.

Virtual Event

Molecular Toxicology Journal Club

EOH student Emily Nicholls will present the article:

"Exposure to air pollution and scarlet fever resurgence in China: a six-year surveillance study"

Liu Y, Ding H, Chang ST, Lu R, Zhong H, Zhao N, Lin TH, Bao Y, Yap L, Xu W, Wang M, Li Y, Qin S, Zhao Y, Geng X, Wang S, Chen E, Yu Z, Chan TC, Liu S

Abstract

Scarlet fever has resurged in China starting in 2011, and the environment is one of the potential reasons. Nationwide data on 655,039 scarlet fever cases and six air pollutants were retrieved. Exposure risks were evaluated by multivariate distributed lag nonlinear models and a meta-regression model. We show that the average incidence in 2011-2018 was twice that in 2004-2010 [RR = 2.30 (4.40 vs. 1.91), 95% CI: 2.29-2.31; p < 0.001] and generally lower in the summer and winter holiday (p = 0.005). A low to moderate correlation was seen between scarlet fever and monthly NO2 (r = 0.21) and O3 (r = 0.11). A 10 μg/m3 increase of NO2 and O3 was significantly associated with scarlet fever, with a cumulative RR of 1.06 (95% CI: 1.02-1.10) and 1.04 (95% CI: 1.01-1.07), respectively, at a lag of 0 to 15 months. In conclusion, long-term exposure to ambient NO2 and O3 may be associated with an increased risk of scarlet fever incidence, but direct causality is not established.


PLEASE SUPPORT OUR STUDENT PRESENTERS

Organized by Dr. Nicholas Fitz of the Department of Environmental and Occupational Health, this weekly course is designed to expose EOH students to the newest and most exciting research in a diverse set of topics related to toxicology.  Guests are welcome.

Dial-In Information

Contact Dr. Nicholas Fitz (nffitz@pitt.edu) for Zoom information to attend.

Thursday, September 24 at 11:00 a.m.

Virtual Event

Event Type

Virtual

Topic

Research