Thursday, September 29, 2022 11:00am to 12:00pm
About this Event
3700 O'Hara Street, Pittsburgh, PA 15261
“Mechanics of Growth, Remodeling, and Failure of Ascending Thoracic Aortic Aneurysm”
ABSTRACT:
Ascending thoracic aortic aneurysm (ATAA), an enlargement of the aorta near its exit from the heart, is largely harmless unless a vessel wall failure event occurs. Such an event, however, is life-threatening and would best be prevented by surgical intervention before the tissue fails. Surgical intervention, while effective, is also costly and dangerous, so the challenge to the biomedical engineer is to develop tools to help identify and quantify the risk to a specific patient based on available information. In collaboration with Jessica Wagenseil at Washington University, we are employing a combination of mouse models, computer models, and ex vivo experiments to understand how ATAAs grow and rupture, with the eventual goal of patient-specific predictive models. We are still a ways away, but the journey so far has been interesting and informative.
BIOGRAPHY:
Victor Barocas is a Professor of Biomedical Engineering at the University of Minnesota, with a strong interest in soft-tissue biomechanics and mechanobiology. Over the last two decades, he has studied a wide range of organs and tissues, including the eye, the kidneys, the spine, and the cardiovascular system. His work involves a combination of experimental and computational methods. From 2012-2022, he served as the co-Editor-in-Chief of the ASME Journal of Biomechanical Engineering.
Please let us know if you require an accommodation in order to participate in this event. Accommodations may include live captioning, ASL interpreters, and/or captioned media and accessible documents from recorded events. At least 5 days in advance is recommended.