10
Nov
Masahiro Shuda, PhD
Assistant Professor
Department of Microbiology & Molecular Genetics
University of Pittsburgh
Tumor virus research has provided a wealth of information for cancer biology. Polyomaviruses
in particular have been central to understanding basic mechanisms of cancer cell transformation. Studies on the SV40 T antigen, for example, led to the discovery of p53 and uncovered the functions of retinoblastoma tumor suppressor protein in cell cycle regulation. Research on murine polyomavirus led to the discovery of tyrosine phosphorylation and the phosphoinositide 3-kinase signaling pathway. Each new cancer virus provides a new model for investigating basic pathways in carcinogenesis. My research exploits the most recently discovered human tumor virus, Merkel cell polyomavirus (MCV), to identify novel cellular pathways leading to cancer.
Contact Judy Malenka at jmalenka@pitt.edu for Zoom information.
Wednesday, November 10 at 12:00 p.m. to 1:00 p.m.
Pitt Public Health, Room A115 130 DeSoto Street
Masahiro Shuda, PhD
Assistant Professor
Department of Microbiology & Molecular Genetics
University of Pittsburgh
Tumor virus research has provided a wealth of information for cancer biology. Polyomaviruses
in particular have been central to understanding basic mechanisms of cancer cell transformation. Studies on the SV40 T antigen, for example, led to the discovery of p53 and uncovered the functions of retinoblastoma tumor suppressor protein in cell cycle regulation. Research on murine polyomavirus led to the discovery of tyrosine phosphorylation and the phosphoinositide 3-kinase signaling pathway. Each new cancer virus provides a new model for investigating basic pathways in carcinogenesis. My research exploits the most recently discovered human tumor virus, Merkel cell polyomavirus (MCV), to identify novel cellular pathways leading to cancer.
Contact Judy Malenka at jmalenka@pitt.edu for Zoom information.
Wednesday, November 10 at 12:00 p.m. to 1:00 p.m.
Pitt Public Health, Room A115 130 DeSoto Street