Presented by Marnie Bertolet, PhD, Associate Professor, Departments of Epidemiology, Biostatistics, and
The Clinical and Translational Science Institute

Simulations can be a powerful tool to help understand quantities that are hard to estimate analytically.  This seminar will demonstrate the use of simulations for two recent trials to aid in determining key parameters for covariate adaptive randomization and interim monitoring.  Dr. Marnie Bertolet is an Associate Professor in the department of Epidemiology.  She earned her PhD in Statistics from Carnegie Mellon, where the phrase “If you cannot estimate, then simulate” was used often. Dr. Bertolet’s collaborative research focuses on clinical trials, including the current MINT trial (blood transfusion thresholds in participants who have had a myocardial infarction and subsequent anemia on outcomes of death and recurrent MI) and the SCD-CARRE (protocolized exchange transfusion versus usual care in participants with Sickle Cell Disease on outcomes number of health care encounters and death) which she will discuss today.

Medical Professionals receive CME credit by texting GOPKUH to 412-312-4424 during the seminar. Course Attendance is recorded through zoom for both students and GSR’s. Students and GSR’s attending in person should swipe their Panther ID at the bottom entrance to G23 to register their attendance. Students should come prepared with engaging questions for the presenters. Students not registered for the course, postdocs, & faculty are welcome to participate.