Guang Li, Assistant Professor, Department of Cell Biology

Cardiac development, a pivotal embryonic process, is intricately controlled at the cellular and molecular levels. Any deviation from the norm in this process can result in congenital heart diseases (CHD), contributing significantly to stillbirths and affecting 1-2% of live births. In my presentation, I will delve into our recently established extensive single-cell RNA-seq dataset and discuss various related studies. Additionally, I will showcase our work on modeling Ebstein's anomaly, a specific congenital heart defect, using patient-derived induced pluripotent stem cells (iPSCs).