Events Calendar

22 Feb
Connecting Protein Structure, Function, and Interfacial Dynamics with Single-Molecule Methods
Event Type

Lectures, Symposia, Etc.

Topic

Research, Innovation, Technology

Target Audience

Graduate Students

Website

https://www.engineering.pitt.edu/Depa...

University Unit
Department of Chemical and Petroleum Engineering
Hashtag

#ChemePitt

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Connecting Protein Structure, Function, and Interfacial Dynamics with Single-Molecule Methods

Graduate Seminar hosted by the Department of Chemical and Petroleum Engineering

Joel L. Kaar
Associate Professor, Department of Chemical and Biological Engineering, University of Colorado, Boulder

Abstract: Our group is broadly focused on understanding and controlling the intersection of biology and materials at the molecular level. This intersection is critical in many areas of biotechnology where proteins and enzymes are integrated into or in constant contact with materials, including biocatalysis, tissue engineering, drug delivery, biosensing, and therapeutic protein formulation. In line with this interest, we have developed a novel approach to elucidate the structure and transient behavior of protein molecules at the solution-solid interface based on dynamic single-molecule tracking. This approach, which is uniquely sensitive to structural and interfacial dynamics, includes the use of high-throughput tracking of protein molecules by means of internal reflection fluorescence (TIRF) microscopy in combination with intramolecular as well as intermolecular Forster resonance energy transfer (FRET)... more

Friday, February 22 at 9:30 a.m. to 10:30 a.m.

Benedum Hall, 102
3700 O'Hara Street, Pittsburgh, PA 15261