Xiangyun Wei, PhD Associate Professor Department of Ophthalmology University of Pittsburgh

Distinct tissue architectures arise when cells are organized in specific orientations relative to neighboring cells. These orientational intercellular relationships are established and maintained by various ‘orientational cell adhesions’ (OCAs). Thus, during tissue morphogenesis, the orientational intercellular relationships and cell adhesions are inherently coupled. OCAs in three tissue and cellular contexts will be discussed, illustrating a new perspective to study tissue morphogenesis.  

HOST:  Alexander D. Sorkin, PhD