Events Calendar

12 Apr
2024 CC Li Memorial Lecture - Alicia Martin, PhD
Event Type

Lectures, Symposia, Etc.

Topic

Research

Target Audience

Faculty, Graduate Students, Postdocs

Tags

Public Health Grand Rounds

University Unit
Department of Human Genetics
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2024 CC Li Memorial Lecture - Alicia Martin, PhD

This is a past event.

 Alicia Martin, PhD
Assistant Investigator
Analytic and Translational Genetics Unit
Massachusetts General Hospital 
Assistant Professor, Harvard Medical School
Associate Member, Broad Institute

Genomics for the world: a comprehensive framework for genetic studies in diverse populations

Genomic studies have matured over the last decade and are poised to improve biomedical outcomes via precision medicine. The primary ethical and scientific obstacle preventing their imminent and routine translation, however, is that they are vastly Eurocentric—current studies would provide systematically greater benefits to European descent populations than to those already most underserved. Moreover, multi-ethnic studies create major scientific opportunities missed by Eurocentric studies. They uniquely inform the extent to which heritable and environmental factors are shared or population specific. To realize equitable benefits of genetics in precision medicine, we are developing analytical methods, tools, community resources, and massive data analyses to facilitate genetic studies across diverse ancestries. In this talk, I will focus on work advancing gene-discovery efforts in globally diverse populations using large-scale meta-analysis across global biobanks. Additionally, I will describe work underway setting up the largest genetic studies of psychiatric phenotypes in underrepresented populations, including over 120,000 participants spanning Latin America and Africa. Lastly, I will describe work evaluating how genetic and exposure risks together predict disease outcomes in diverse populations. 
 

Friday, April 12 at 12:00 p.m. to 1:00 p.m.

Public Health, A115
130 Desoto Street, Pittsburgh, 15261

2024 CC Li Memorial Lecture - Alicia Martin, PhD

 Alicia Martin, PhD
Assistant Investigator
Analytic and Translational Genetics Unit
Massachusetts General Hospital 
Assistant Professor, Harvard Medical School
Associate Member, Broad Institute

Genomics for the world: a comprehensive framework for genetic studies in diverse populations

Genomic studies have matured over the last decade and are poised to improve biomedical outcomes via precision medicine. The primary ethical and scientific obstacle preventing their imminent and routine translation, however, is that they are vastly Eurocentric—current studies would provide systematically greater benefits to European descent populations than to those already most underserved. Moreover, multi-ethnic studies create major scientific opportunities missed by Eurocentric studies. They uniquely inform the extent to which heritable and environmental factors are shared or population specific. To realize equitable benefits of genetics in precision medicine, we are developing analytical methods, tools, community resources, and massive data analyses to facilitate genetic studies across diverse ancestries. In this talk, I will focus on work advancing gene-discovery efforts in globally diverse populations using large-scale meta-analysis across global biobanks. Additionally, I will describe work underway setting up the largest genetic studies of psychiatric phenotypes in underrepresented populations, including over 120,000 participants spanning Latin America and Africa. Lastly, I will describe work evaluating how genetic and exposure risks together predict disease outcomes in diverse populations. 
 

Friday, April 12 at 12:00 p.m. to 1:00 p.m.

Public Health, A115
130 Desoto Street, Pittsburgh, 15261

Topic

Research

Target Audience

Faculty, Graduate Students, Postdocs

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